Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27335841
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
The Evolution of Transjugular Intrahepatic Portosystemic Shunt: Tips
#MMPMID27335841
Fanelli F
ISRN Hepatol
2014[]; 2014
(?): 762096
PMID27335841
show ga
Since Richter's description in the literature in 1989 of the first procedure on
human patients, transjugular intrahepatic portosystemic shunt (TIPS) has been
worldwide considered as a noninvasive technique to manage portal hypertension
complications. TIPS succeeds in lowering the hepatic sinusoidal pressure and in
increasing the circulatory flow, thus reducing sodium retention, ascites
recurrence, and variceal bleeding. Required several revisions of the shunt TIPS
can be performed in case of different conditions such as hepatorenal syndrome,
hepatichydrothorax, portal vein thrombosis, and Budd-Chiari syndrome. Most of the
previous studies on TIPS procedure were based on the use of bare stents and most
patients chose TIPS 2-3 years after traditional treatment, thus making TIPS
appear to be not superior to endoscopy in survival rates. Bare stents were
associated with higher incidence of shunt failure and consequently patients
required several revisions during the follow-up. With the introduction of a
dedicated e-PTFE covered stent-graft, these problems were completely solved, No
more reinterventions are required with a tremendous improvement of patient's
quality of life. One of the main drawbacks of the use of e-PTFE covered
stent-graft is higher incidence of hepatic encephalopathy. In those cases
refractory to the conventional medical therapy, a shunt reduction must be
performed.
free
free
free
