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2015 ; 172
(24
): 5979-6023
Nephropedia Template TP
gab.com Text
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English Wikipedia
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors
#MMPMID26650444
Alexander SP
; Fabbro D
; Kelly E
; Marrion N
; Peters JA
; Benson HE
; Faccenda E
; Pawson AJ
; Sharman JL
; Southan C
; Davies JA
Br J Pharmacol
2015[Dec]; 172
(24
): 5979-6023
PMID26650444
show ga
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key
properties of over 1750 human drug targets with their pharmacology, plus links to
an open access knowledgebase of drug targets and their ligands
(www.guidetopharmacology.org), which provides more detailed views of target and
ligand properties. The full contents can be found at
http://onlinelibrary.wiley.com/doi/10.1111/bph.13353/full. G protein-coupled
receptors are one of the eight major pharmacological targets into which the Guide
is divided, with the others being: G protein-coupled receptors, ligand-gated ion
channels, voltage-gated ion channels, other ion channels, nuclear hormone
receptors, enzymes and transporters. These are presented with nomenclature
guidance and summary information on the best available pharmacological tools,
alongside key references and suggestions for further reading. The Concise Guide
is published in landscape format in order to facilitate comparison of related
targets. It is a condensed version of material contemporary to late 2015, which
is presented in greater detail and constantly updated on the website
www.guidetopharmacology.org, superseding data presented in the previous Guides to
Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is
produced in conjunction with NC-IUPHAR and provides the official IUPHAR
classification and nomenclature for human drug targets, where appropriate. It
consolidates information previously curated and displayed separately in IUPHAR-DB
and GRAC and provides a permanent, citable, point-in-time record that will
survive database updates.