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10.1155/2015/272359 http://scihub22266oqcxt.onion/10.1155/2015/272359 C4496485!4496485 !26199948     free     free     free       J+Immunol+Res 2015 ; 2015 (?): 272359 Nephropedia Template TP {{tp|p=26199948 |t=2015. The Complex Role of STAT3 in Viral Infections |pdf=|usr=}}{{26199948 }} gab.com Text The Complex Role of STAT3 in Viral Infections JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=26199948 #FOAvip Signal transducer and activators of transcription-3 (STAT3) regulates diverse biological functions including cell growth, differentiation, and apoptosis. In addition, STAT3 plays a key role in regulating host immune and inflammatory responses and in the pathogenesis of many cancers. Several studies reported differential regulation of STAT3 in a range of viral infections. Interestingly, STAT3 appears to direct seemingly contradictory responses and both pro- and antiviral roles of STAT3 have been described. This review summarized the currently known functions of STAT3 in the regulation of viral replication and pathogenesis of viral infections. Some of the key unanswered questions and the gap in our current understanding of the role of STAT3 in viral pathogenesis are discussed. Twit Text FOAVip The Complex Role of STAT3 in Viral Infections ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=26199948 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26199948 #FOAvip English Wikipedia <ref>{{Cite pmid|26199948 }}</ref> The Complex Role of STAT3 in Viral Infections #MMPMID26199948 Kuchipudi SV J Immunol Res 2015[]; 2015 (?): 272359 PMID26199948 show ga Signal transducer and activators of transcription-3 (STAT3) regulates diverse biological functions including cell growth, differentiation, and apoptosis. In addition, STAT3 plays a key role in regulating host immune and inflammatory responses and in the pathogenesis of many cancers. Several studies reported differential regulation of STAT3 in a range of viral infections. Interestingly, STAT3 appears to direct seemingly contradictory responses and both pro- and antiviral roles of STAT3 have been described. This review summarized the currently known functions of STAT3 in the regulation of viral replication and pathogenesis of viral infections. Some of the key unanswered questions and the gap in our current understanding of the role of STAT3 in viral pathogenesis are discussed. |Animals [MESH] |Cytokines/metabolism [MESH] |Host-Pathogen Interactions [MESH] |Humans [MESH] |Immunity [MESH] |Janus Kinases/metabolism [MESH] |Protein Binding [MESH] |Protein Interaction Domains and Motifs [MESH] |STAT3 Transcription Factor/chemistry/*metabolism [MESH] |Signal Transduction [MESH] |Virus Diseases/*metabolism/virology [MESH] |Virus Physiological Phenomena [MESH]The Complex Role of STAT3 in Viral Infections (epmc).pdf DeepDyve Pubget Overpricing