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10.1016/j.molmed.2017.05.008

http://scihub22266oqcxt.onion/10.1016/j.molmed.2017.05.008
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C5515260!5515260 !28583420
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suck abstract from ncbi

pmid28583420
      Trends+Mol+Med 2017 ; 23 (7 ): 580-582
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  • The Boosting Potential of Bacteria in Cancer Immunotherapy #MMPMID28583420
  • Binder DC ; Wainwright DA
  • Trends Mol Med 2017[Jul]; 23 (7 ): 580-582 PMID28583420 show ga
  • Salmonella Typhimurium, engineered to express flagellin B, recently demonstrated unprecedented tumor control through a TLR-dependent mechanism. Here, we review new observations that support the potential of utilizing modified bacteria to enhance antitumor immunity. We also discuss the implications of these findings for clinical applications, including immune checkpoint blockade therapies.
  • |Animals [MESH]
  • |Flagellin/genetics/*immunology/*therapeutic use [MESH]
  • |Humans [MESH]
  • |Immunotherapy/*methods [MESH]
  • |Neoplasms/immunology/*therapy [MESH]
  • |Salmonella typhimurium/genetics/*immunology [MESH]


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