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10.1016/j.bbamcr.2015.04.015 http://scihub22266oqcxt.onion/10.1016/j.bbamcr.2015.04.015 C4846286!4846286!25930943     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25930943.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biochim+Biophys+Acta 2015 ; 1853 (11 Pt B): 3153-64 Nephropedia Template TP {{tp|p=25930943|t=2015. The (dys)functional extracellular matrix? |pdf=|usr=}}{{25930943}} gab.com Text The (dys)functional extracellular matrix JO: Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=25930943 #FOAvip The extracellular matrix (ECM) is a major component of the biomechanical environment with which cells interact, and it plays important roles in both normal development and disease progression. Mechanical and biochemical factors alter the biomechanical properties of tissues by driving cellular remodeling of the ECM. This review provides an overview of the structural, compositional, and mechanical properties of the ECM that instruct cell behaviors. Case studies are reviewed that highlight mechanotransduction in the context of two distinct tissues: tendons and the heart. Although these two tissues demonstrate differences in relative cell?ECM composition and mechanical environment, they share similar mechanisms underlying ECM dysfunction and cell mechanotransduction. Together, these topics provide a framework for a fundamental understanding of the ECM and how it may vary across normal and diseased tissues in response to mechanical and biochemical cues. This article is part of a Special Issue entitled: Mechanobiology. Twit Text FOAVip The (dys)functional extracellular matrix ????Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=25930943 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25930943 #FOAvip English Wikipedia <ref>{{Cite pmid|25930943}}</ref> The (dys)functional extracellular matrix? #MMPMID25930943 Freedman BR; Bade ND; Riggin CN; Zhang S; Haines PG; Ong KL; Janmey PA Biochim Biophys Acta 2015[Nov]; 1853 (11 Pt B): 3153-64 PMID25930943show ga The extracellular matrix (ECM) is a major component of the biomechanical environment with which cells interact, and it plays important roles in both normal development and disease progression. Mechanical and biochemical factors alter the biomechanical properties of tissues by driving cellular remodeling of the ECM. This review provides an overview of the structural, compositional, and mechanical properties of the ECM that instruct cell behaviors. Case studies are reviewed that highlight mechanotransduction in the context of two distinct tissues: tendons and the heart. Although these two tissues demonstrate differences in relative cell?ECM composition and mechanical environment, they share similar mechanisms underlying ECM dysfunction and cell mechanotransduction. Together, these topics provide a framework for a fundamental understanding of the ECM and how it may vary across normal and diseased tissues in response to mechanical and biochemical cues. This article is part of a Special Issue entitled: Mechanobiology. äThe (dys)functional extracellular matrix? (epmc).pdf DeepDyve Pubget Overpricing