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Thalassemia review: features, dental considerations and management
#MMPMID28461877
Helmi N
; Bashir M
; Shireen A
; Ahmed IM
Electron Physician
2017[Mar]; 9
(3
): 4003-4008
PMID28461877
show ga
Thalassemia is a genetic disorder that involves abnormal haemoglobin formation.
The two main categories of thalassemia are alpha and beta thalassemia that are
then divided into further subcategories. While some mild forms of thalassemia
might even go unnoticed and only cause mild anaemia and iron deficiency problems
in patients, other more severe forms of thalassemia can even result in death.
Individuals with thalassemia can get treatment according to the level of severity
of their condition. The main oral manifestations of thalassemia are Class II
malocclusion, maxillary protrusion, high caries index, severe gingivitis. Any
dental surgical procedure for such patients should be done under antibiotic cover
and immediately after transfusion. Caution should be exercised in thalassemia
patients due to complications related to compromised immunity and cardiovascular
issues. Multidisciplinary approach involving dental surgeon, haematologist and
orthodontist is the best advised approach.
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