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10.3389/fcell.2017.00034 http://scihub22266oqcxt.onion/10.3389/fcell.2017.00034 C5382171!5382171 !28428953     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28428953 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28428953 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Front+Cell+Dev+Biol 2017 ; 5 (ä): 34 Nephropedia Template TP {{tp|p=28428953 |t=2017. Tetraspanins Function as Regulators of Cellular Signaling |pdf=|usr=}}{{28428953 }} gab.com Text Tetraspanins Function as Regulators of Cellular Signaling JO: Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28428953 #FOAvip Tetraspanins are molecular scaffolds that distribute proteins into highly organized microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have identified interactions between tetraspanins and signaling molecules, finding unique downstream cellular consequences. In this review, we will explore these interactions as well as the specific cellular responses to signal activation, focusing on tetraspanin regulation of adhesion-mediated (integrins/FAK), receptor-mediated (EGFR, TNF-?, c-Met, c-Kit), and intracellular signaling (PKC, PI4K, ?-catenin). Additionally, we will summarize our current understanding for how tetraspanin post-translational modifications (palmitoylation, N-linked glycosylation, and ubiquitination) can regulate signal propagation. Many of the studies outlined in this review suggest that tetraspanins offer a potential therapeutic target to modulate aberrant signal transduction pathways that directly impact a host of cellular behaviors and disease states. Twit Text FOAVip Tetraspanins Function as Regulators of Cellular Signaling ????Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28428953 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28428953 #FOAvip English Wikipedia <ref>{{Cite pmid|28428953 }}</ref> Tetraspanins Function as Regulators of Cellular Signaling #MMPMID28428953 Termini CM ; Gillette JM Front Cell Dev Biol 2017[]; 5 (ä): 34 PMID28428953 show ga Tetraspanins are molecular scaffolds that distribute proteins into highly organized microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have identified interactions between tetraspanins and signaling molecules, finding unique downstream cellular consequences. In this review, we will explore these interactions as well as the specific cellular responses to signal activation, focusing on tetraspanin regulation of adhesion-mediated (integrins/FAK), receptor-mediated (EGFR, TNF-?, c-Met, c-Kit), and intracellular signaling (PKC, PI4K, ?-catenin). Additionally, we will summarize our current understanding for how tetraspanin post-translational modifications (palmitoylation, N-linked glycosylation, and ubiquitination) can regulate signal propagation. Many of the studies outlined in this review suggest that tetraspanins offer a potential therapeutic target to modulate aberrant signal transduction pathways that directly impact a host of cellular behaviors and disease states. äTetraspanins Function as Regulators of Cellular Signaling (epmc).pdf DeepDyve Pubget Overpricing