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10.4161/19336918.2014.987587

http://scihub22266oqcxt.onion/10.4161/19336918.2014.987587
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suck abstract from ncbi


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pmid25482829
      Cell+Adh+Migr 2015 ; 9 (1-2 ): 48-82
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  • Tenascin-C: Form versus function #MMPMID25482829
  • Giblin SP ; Midwood KS
  • Cell Adh Migr 2015[]; 9 (1-2 ): 48-82 PMID25482829 show ga
  • Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very restricted pattern of expression but an enormously diverse range of functions. Here, we discuss the importance of deciphering the expression pattern of, and effects mediated by, different forms of this molecule in order to fully understand tenascin-C biology. We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic cleavage, highlighting how these modifications are key to defining tenascin-C function.
  • |Animals [MESH]
  • |Brain/*metabolism [MESH]
  • |Gene Expression Regulation/*physiology [MESH]
  • |Gene Regulatory Networks/*physiology [MESH]
  • |Humans [MESH]
  • |Protein Processing, Post-Translational/physiology [MESH]
  • |Signal Transduction/*physiology [MESH]


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