Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23241355
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23241355
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Cell+Mol+Med
2012 ; 16
(12
): 3116-22
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Telocytes in the human kidney cortex
#MMPMID23241355
Qi G
; Lin M
; Xu M
; Manole CG
; Wang X
; Zhu T
J Cell Mol Med
2012[Dec]; 16
(12
): 3116-22
PMID23241355
show ga
Renal interstitial cells play an important role in the physiology and pathology
of the kidneys. As a novel type of interstitial cell, telocytes (TCs) have been
described in various tissues and organs, including the heart, lung, skeletal
muscle, urinary tract, etc. (www.telocytes.com). However, it is not known if TCs
are present in the kidney interstitium. We demonstrated the presence of TCs in
human kidney cortex interstitium using primary cell culture, transmission
electron microscopy (TEM) and in situ immunohistochemistry (IHC). Renal TCs were
positive for CD34, CD117 and vimentin. They were localized in the kidney cortex
interstitial compartment, partially covering the tubules and vascular walls.
Morphologically, renal TCs resemble TCs described in other organs, with very long
telopodes (Tps) composed of thin segments (podomers) and dilated segments
(podoms). However, their possible roles (beyond intercellular signalling) as well
as their specific phenotype in the kidney remain to be established.
free
free
free
