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2014 ; 18
(6
): 975-8
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Telocytes in mice bone marrow: electron microscope evidence
#MMPMID25059385
Li H
; Zhang H
; Yang L
; Lu S
; Ge J
J Cell Mol Med
2014[Jun]; 18
(6
): 975-8
PMID25059385
show ga
Telocytes (TCs) are a novel type of interstitial cell of whom presence has been
recently documented in many tissues and organs. However, whether TCs exists in
bone marrow is still not reported. This study aims to find out TCs in mice bone
marrow by using scanning electron microscope (SEM) and transmission electron
microscope (TEM). SEM images showed that in mice bone marrow most of TCs have
small spherical cell body (usually 4-6 ?m diameter) with thin long telopodes
(Tps; usually one to three). The longest Tp observed was about 70 ?m, with an
uneven calibre. Direct intercellular contacts exist between TCs. TEM shows
mitochondria within dilations of Tps. Also, by TEM, we show the close spatial
relations of Tps with blood vessels. In conclusion, this study provides
ultrastructural evidence regarding the existence of TCs in mice bone marrow, in
situ.