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2016 ; 17
(8
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
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English Wikipedia
Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses
#MMPMID27529228
Cretoiu D
; Xu J
; Xiao J
; Cretoiu SM
Int J Mol Sci
2016[Aug]; 17
(8
): ä PMID27529228
show ga
Entering the new millennium, nobody believed that there was the possibility of
discovering a new cellular type. Nevertheless, telocytes (TCs) were described as
a novel kind of interstitial cell. Ubiquitously distributed in the extracellular
matrix of any tissue, TCs are regarded as cells with telopodes involved in
intercellular communication by direct homo- and heterocellular junctions or by
extracellular vesicle (EVs) release. Their discovery has aroused the interest of
many research groups worldwide, and many researchers regard them as potentially
regenerative cells. Given the experience of our laboratory, where these cells
were first described, we review the evidence supporting the fact that TCs release
EVs, and discuss alternative hypotheses about their future implications.