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10.1186/2052-8426-2-28 http://scihub22266oqcxt.onion/10.1186/2052-8426-2-28 C4452063!4452063 !26056595     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26056595 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Cell+Ther 2014 ; 2 (ä): 28 Nephropedia Template TP {{tp|p=26056595 |t=2014. Targeting the Wnt pathways for therapies |pdf=|usr=}}{{26056595 }} gab.com Text Targeting the Wnt pathways for therapies JO: Mol Cell Ther http://www.kidney.de/pget.php?&tw=1&pmid=26056595 #FOAvip The Wnt/?-catenin signaling pathway is crucial in animal development from sponges to humans. Its activity in the adulthood is less general, with exceptions having huge medical importance. Namely, improper activation of this pathway is carcinogenic in many tissues, most notably in the colon, liver and the breast. On the other hand, the Wnt/?-catenin signaling must be re-activated in cases of tissue damage, and insufficient activation results in regeneration failure and degeneration. These both medically important implications are unified by the emerging importance of this signaling pathway in the control of proliferation of various types of stem cells, crucial for tissue regeneration and, in case of cancer stem cells - cancer progression and relapse. This article aims at briefly reviewing the current state of knowledge in the field of Wnt signaling, followed by a detailed discussion of current medical developments targeting distinct branches of the Wnt pathway for anti-cancer and pro-regeneration therapies. Twit Text FOAVip Targeting the Wnt pathways for therapies ????Mol Cell Ther http://www.kidney.de/pget.php?&tw=1&pmid=26056595 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26056595 #FOAvip English Wikipedia <ref>{{Cite pmid|26056595 }}</ref> Targeting the Wnt pathways for therapies #MMPMID26056595 Blagodatski A ; Poteryaev D ; Katanaev VL Mol Cell Ther 2014[]; 2 (ä): 28 PMID26056595 show ga The Wnt/?-catenin signaling pathway is crucial in animal development from sponges to humans. Its activity in the adulthood is less general, with exceptions having huge medical importance. Namely, improper activation of this pathway is carcinogenic in many tissues, most notably in the colon, liver and the breast. On the other hand, the Wnt/?-catenin signaling must be re-activated in cases of tissue damage, and insufficient activation results in regeneration failure and degeneration. These both medically important implications are unified by the emerging importance of this signaling pathway in the control of proliferation of various types of stem cells, crucial for tissue regeneration and, in case of cancer stem cells - cancer progression and relapse. This article aims at briefly reviewing the current state of knowledge in the field of Wnt signaling, followed by a detailed discussion of current medical developments targeting distinct branches of the Wnt pathway for anti-cancer and pro-regeneration therapies. äTargeting the Wnt pathways for therapies (epmc).pdf DeepDyve Pubget Overpricing