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10.1091/mbc.E15-05-0311

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pmid27634743
      Mol+Biol+Cell 2016 ; 27 (18 ): 2804-6
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  • TOR and paradigm change: cell growth is controlled #MMPMID27634743
  • Hall MN
  • Mol Biol Cell 2016[Sep]; 27 (18 ): 2804-6 PMID27634743 show ga
  • This year marks the 25th anniversary of the discovery of target of rapamycin (TOR), a highly conserved kinase and central controller of cell growth. In this Retrospective, I briefly describe the discovery of TOR and the subsequent elucidation of its cellular role. I place particular emphasis on an article by Barbet et al. from 1996, the first suggesting that TOR controls cell growth in response to nutrients.
  • |Cell Cycle [MESH]
  • |Cell Division [MESH]
  • |Cell Proliferation [MESH]
  • |Humans [MESH]
  • |Signal Transduction/physiology [MESH]
  • |Sirolimus [MESH]


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