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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Magn+Reson+Imaging
2015 ; 41
(3
): 586-600
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T?? MRI of human musculoskeletal system
#MMPMID24935818
Wang L
; Regatte RR
J Magn Reson Imaging
2015[Mar]; 41
(3
): 586-600
PMID24935818
show ga
Magnetic resonance imaging (MRI) offers the direct visualization of the human
musculoskeletal (MSK) system, especially all diarthrodial tissues including
cartilage, bone, menisci, ligaments, tendon, hip, synovium, etc. Conventional MRI
techniques based on T1 - and T2 -weighted, proton density (PD) contrast are
inconclusive in quantifying early biochemically degenerative changes in MSK
system in general and articular cartilage in particular. In recent years,
quantitative MR parameter mapping techniques have been used to quantify the
biochemical changes in articular cartilage, with a special emphasis on evaluating
joint injury, cartilage degeneration, and soft tissue repair. In this article we
focus on cartilage biochemical composition, basic principles of T1? MRI,
implementation of T1? pulse sequences, biochemical validation, and summarize the
potential applications of the T1? MRI technique in MSK diseases including
osteoarthritis (OA), anterior cruciate ligament (ACL) injury, and knee joint
repair. Finally, we also review the potential advantages, challenges, and future
prospects of T1? MRI for widespread clinical translation.