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10.1002/wsbm.1382

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suck abstract from ncbi


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pmid28221004
      Wiley+Interdiscip+Rev+Syst+Biol+Med 2017 ; 9 (4 ): ä
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  • Systems biology of oxygen homeostasis #MMPMID28221004
  • Samanta D ; Prabhakar NR ; Semenza GL
  • Wiley Interdiscip Rev Syst Biol Med 2017[Jul]; 9 (4 ): ä PMID28221004 show ga
  • Metazoan species maintain oxygen homeostasis through the activity of hypoxia-inducible factors, which are transcriptional activators that regulate the expression of hundreds of genes to match O(2) supply and demand. Here, we review the involvement of hypoxia-inducible factors in the molecular physiology and pathophysiology of cellular O(2) sensing, O(2) delivery, O(2) utilization, and systemic O(2) sensing. WIREs Syst Biol Med 2017, 9:e1382. doi: 10.1002/wsbm.1382 For further resources related to this article, please visit the WIREs website.
  • |*Models, Cardiovascular [MESH]
  • |*Systems Biology [MESH]
  • |Homeostasis/*physiology [MESH]
  • |Humans [MESH]


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