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10.1002/hep.27023

http://scihub22266oqcxt.onion/10.1002/hep.27023
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C4105331!4105331 !24449428
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suck abstract from ncbi


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pmid24449428
      Hepatology 2014 ; 60 (2 ): 736-43
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  • Systems biology for hepatologists #MMPMID24449428
  • Mato JM ; Martínez-Chantar ML ; Lu SC
  • Hepatology 2014[Aug]; 60 (2 ): 736-43 PMID24449428 show ga
  • Medicine is expected to benefit from combining usual cellular and molecular studies with high-throughput methods (genomics, transcriptomics, proteomics, and metabolomics). These methods, collectively known as omics, permit the determination of thousands of molecules (variations within genes, RNAs, proteins, metabolites) within a tissue, cell, or biological fluid. The use of these methods is very demanding in terms of the design of the study, acquisition, storage, analysis, and interpretation of the data. When carried out properly, these studies can reveal new etiological pathways, help to identify patients at risk for disease, and predict the response to specific treatments. Here we review these omics methods and mention several applications in hepatology research.
  • |*Liver Diseases/diagnosis/physiopathology/therapy [MESH]
  • |Gastroenterology/*methods/*trends [MESH]
  • |Genomics/methods/trends [MESH]
  • |Humans [MESH]
  • |Metabolomics/methods/trends [MESH]
  • |Proteomics/methods/trends [MESH]


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