Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\21601676
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Methods+Enzymol
2011 ; 498
(ä): 137-52
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
SynBioSS-aided design of synthetic biological constructs
#MMPMID21601676
Kaznessis YN
Methods Enzymol
2011[]; 498
(ä): 137-52
PMID21601676
show ga
We present walkthrough examples of using SynBioSS to design, model, and simulate
synthetic gene regulatory networks. SynBioSS stands for Synthetic Biology
Software Suite, a platform that is publicly available with Open Licenses at
www.synbioss.org. An important aim of computational synthetic biology is the
development of a mathematical modeling formalism that is applicable to a wide
variety of simple synthetic biological constructs. SynBioSS-based modeling of
biomolecular ensembles that interact away from the thermodynamic limit and not
necessarily at steady state affords for a theoretical framework that is generally
applicable to known synthetic biological systems, such as bistable switches, AND
gates, and oscillators. Here, we discuss how SynBioSS creates links between DNA
sequences and targeted dynamic phenotypes of these simple systems.