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2017 ; 8
(ä): 1-12
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Swine brucellosis: current perspectives
#MMPMID30050849
Olsen SC
; Tatum FM
Vet Med (Auckl)
2017[]; 8
(ä): 1-12
PMID30050849
show ga
Brucella suis is a significant zoonotic species that is present in domestic
livestock and wildlife in many countries worldwide. Transmission from animal
reservoirs is the source of human infection as human-to-human transmission is
very rare. Although swine brucellosis causes economic losses in domestic
livestock, preventing human infection is the primary reason for its emphasis in
disease control programs. Although disease prevalence varies worldwide, in areas
outside of Europe, swine brucellosis is predominantly caused by B. suis biovars 1
and 3. In Europe, swine are predominantly infected with biovar 2 which is much
less pathogenic in humans. In many areas worldwide, feral or wild populations of
swine are important reservoir hosts. Like other Brucella spp. in their natural
host, B. suis has developed mechanisms to survive in an intracellular environment
and evade immune detection. Limitations in sensitivity and specificity of current
diagnostics require use at a herd level, rather for individual animals. There is
currently no commercial vaccine approved for preventing brucellosis in swine.
Although not feasible in all situations, whole-herd depopulation is the most
effective regulatory mechanism to control swine brucellosis.
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