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2018 ; 10
(4
): 30-45
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Susceptibility weighted imaging: Clinical applications and future directions
#MMPMID29849962
Halefoglu AM
; Yousem DM
World J Radiol
2018[Apr]; 10
(4
): 30-45
PMID29849962
show ga
Susceptibility weighted imaging (SWI) is a recently developed magnetic resonance
imaging (MRI) technique that is increasingly being used to narrow the
differential diagnosis of many neurologic disorders. It exploits the magnetic
susceptibility differences of various compounds including deoxygenated blood,
blood products, iron and calcium, thus enabling a new source of contrast in MR.
In this review, we illustrate its basic clinical applications in neuroimaging.
SWI is based on a fully velocity-compensated, high-resolution, three dimensional
gradient-echo sequence using magnitude and phase images either separately or in
combination with each other, in order to characterize brain tissue. SWI is
particularly useful in the setting of trauma and acute neurologic presentations
suggestive of stroke, but can also characterize occult low-flow vascular
malformations, cerebral microbleeds, intracranial calcifications,
neurodegenerative diseases and brain tumors. Furthermore, advanced MRI
post-processing technique with quantitative susceptibility mapping, enables
detailed anatomical differentiation based on quantification of brain iron from
SWI raw data.