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2017 ; 143
(9
): 1865-1870
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Surgical treatment of advanced penile cancer
#MMPMID28493019
Zhang K
; Wan X
; Xu H
; Li W
; Zhou J
; Xu MX
; Yao HJ
; Wang Z
J Cancer Res Clin Oncol
2017[Sep]; 143
(9
): 1865-1870
PMID28493019
show ga
PURPOSE: To evaluate the therapeutic effect of surgery in patients with advanced
penile cancer, who have a dismal prognosis. PATIENTS AND METHODS: Between
September 2007 and July 2015, we treated 12 patients with surgical therapy.
RESULTS: The median follow-up period for all the patients was 16 months (range
4-60 months). The outcome and concomitant symptoms were analyzed, and the
survival rates were calculated. Three of the patients are currently alive. The
median overall survival of the patients was 9 months (range 4-13 months).
CONCLUSION: The present results suggest that surgery is a valuable treatment
option for patients with advanced penile cancer. The prognosis of advanced penile
cancer is closely related to lymph node and distant metastases. Flap repair can
solve the problem of large area skin defect. Advanced penile cancer is difficult
to treat regardless of chemotherapy or radiotherapy, and surgery cannot prolong
the lives of patients. However, the dissection of lesions and repair of large
area skin defects can dramatically improve the quality of life of patients,
especially those with locally advanced disease without distant metastasis.
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