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2015 ; 2015
(ä): 503109
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Surgical Approaches to Chronic Pancreatitis
#MMPMID26681935
Hartmann D
; Friess H
Gastroenterol Res Pract
2015[]; 2015
(ä): 503109
PMID26681935
show ga
Chronic pancreatitis is a progressive inflammatory disease resulting in permanent
structural damage of the pancreas. It is mainly characterized by recurring
epigastric pain and pancreatic insufficiency. In addition, progression of the
disease might lead to additional complications, such as pseudocyst formation or
development of pancreatic cancer. The medical and surgical treatment of chronic
pancreatitis has changed significantly in the past decades. With regard to
surgical management, pancreatic head resection has been shown to be a mainstay in
the treatment of severe chronic pancreatitis because the pancreatic head mass is
known to trigger the chronic inflammatory process. Over the years,
organ-preserving procedures, such as the duodenum-preserving pancreatic head
resection and the pylorus-preserving Whipple, have become the surgical standard
and have led to major improvements in pain relief, preservation of pancreatic
function, and quality of life of patients.