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10.1146/annurev-nutr-071813-105654

http://scihub22266oqcxt.onion/10.1146/annurev-nutr-071813-105654
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suck abstract from ncbi


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pmid25033061
      Annu+Rev+Nutr 2014 ; 34 (ä): 171-205
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  • Sulfur as a signaling nutrient through hydrogen sulfide #MMPMID25033061
  • Kabil O ; Vitvitsky V ; Banerjee R
  • Annu Rev Nutr 2014[]; 34 (ä): 171-205 PMID25033061 show ga
  • Hydrogen sulfide (H?S) has emerged as an important signaling molecule with beneficial effects on various cellular processes affecting, for example, cardiovascular and neurological functions. The physiological importance of H?S is motivating efforts to develop strategies for modulating its levels. However, advancement in the field of H?S-based therapeutics is hampered by fundamental gaps in our knowledge of how H?S is regulated, its mechanism of action, and its molecular targets. This review provides an overview of sulfur metabolism; describes recent progress that has shed light on the mechanism of H?S as a signaling molecule; and examines nutritional regulation of sulfur metabolism, which pertains to health and disease.
  • |*Diet [MESH]
  • |*Models, Biological [MESH]
  • |*Signal Transduction [MESH]
  • |Aging/metabolism [MESH]
  • |Amino Acids, Sulfur/metabolism [MESH]
  • |Animals [MESH]
  • |Cardiovascular System/enzymology/metabolism [MESH]
  • |Central Nervous System/blood supply/enzymology/metabolism [MESH]
  • |Endoplasmic Reticulum Stress [MESH]
  • |Endothelium, Vascular/enzymology/*metabolism [MESH]
  • |Humans [MESH]
  • |Hydrogen Sulfide/*metabolism [MESH]
  • |Nutritional Requirements [MESH]
  • |Sulfur Compounds/*metabolism [MESH]


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