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2017 ; 21
(3
): 213-223
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Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases
#MMPMID28680488
Rossini BAA
; Penido NO
; Munhoz MSL
; Bogaz EA
; Curi RS
Int Arch Otorhinolaryngol
2017[Jul]; 21
(3
): 213-223
PMID28680488
show ga
Introduction ?Several authors have demonstrated the relationship between sudden
sensorineural hearing loss (SNHL) and systemic autoimmune diseases (SAD).
Immune-mediated SNHL can rarely present as unilateral sudden SNHL and manifests
itself in the contralateral ear only after years. It presents clinical relevance
for being one of the few SNHL that may be reversible given that early and
appropriate treatment is applied. Objective ?The objective of this study is to
describe the clinical presentations and audiological findings from patients with
idiopathic sudden SNHL and SAD associated with a probable diagnosis of
immune-mediated SNHL. Furthermore, we strive to estimate the prevalence of SAD in
patients with sudden SNHL. Methods ?This is an observational retrospective
cohort. We have selected and studied patients with SAD. Revision of available
literature on scientific repositories. Results ?We evaluated 339 patients with
sudden SNHL. Among them, 13 (3.83%) patients suffered from SAD. Three patients
had bilateral involvement, a total of 16 ears. We evaluate and describe various
clinical, epidemiological, and audiological aspects of this sample. Conclusion
?In our sample of patients with sudden SNHL, the prevalence of SAD was found
relevant. The majority had tinnitus and dizziness concomitant hearing loss,
unilateral involvement and had experienced profound hearing loss at the time of
the installation. In spite of instituted treatment, most cases showed no
improvement in audiometric thresholds. Apparently, patients with sudden SNHL and
SAD have a more severe initial impairment, higher percentage of bilateral, lower
response to treatment, and worse prognosis than patients with sudden SNHL of
unknown etiology.