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2018 ; 10
(3
): e2307
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Subungual Amelanotic Melanoma Masquerading as Onychomycosis
#MMPMID29755903
Riahi RR
; Cohen PR
; Goldberg LH
Cureus
2018[Mar]; 10
(3
): e2307
PMID29755903
show ga
Subungual amelanotic melanoma is rare. In addition, amelanotic melanoma can mimic
non-melanocytic tumors. A 67-year-old woman had a four-year history of dystrophy
of the left fourth fingernail. Periodic acid-Schiff staining of the nail plate
demonstrated fungal hyphae, establishing a diagnosis of tinea unguium. The nail
plate subsequently detached and the underlying nail bed showed a red, friable
mass that was biopsied and confirmed a diagnosis of melanoma. In conclusion,
additional morphologic change of a persistent nail dystrophy-even with a
biopsy-confirmed diagnosis of onychomycosis-may require consideration for repeat
evaluation, including a biopsy, to exclude the possibility of a subungual
malignant tumor.