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2016 ; 8
(Suppl 6
): S517-27
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Stereotactic body radiotherapy: current strategies and future development
#MMPMID27606082
Tsang MW
J Thorac Dis
2016[Jul]; 8
(Suppl 6
): S517-27
PMID27606082
show ga
Stereotactic body radiotherapy (SBRT) has emerged as the standard treatment for
medically inoperable early-staged non-small cell lung cancer (NSCLC). The local
control rate after SBRT is over 90%. Some forms of tumour motion management and
image-guided radiation delivery techniques are the prerequisites for fulfilment
of its goal to deliver a high radiation dose to the tumour target without
overdosing surrounding normal tissues. In this review, the current strategies of
tumour motion management will be discussed, followed by an overview of various
image-guided radiotherapy (RT) systems and devices available for clinical
practice. Besides medically inoperable stage I NSCLC, SBRT has also been widely
adopted for treatment of oligometastasis involving the lungs. Its possible
applications in various other cancer illnesses are under extensive exploration.
The progress of SBRT is critically technology-dependent. With advancement of
technology, the ideal of personalised, effective and yet safe SBRT is already on
the horizon.