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2014 ; 5
(3
): 190-7
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Stereotactic body radiation therapy for liver metastases
#MMPMID24982767
Scorsetti M
; Clerici E
; Comito T
J Gastrointest Oncol
2014[Jun]; 5
(3
): 190-7
PMID24982767
show ga
Over the years, early diagnosis of metastatic disease has improved and the
prevalence of oligometastatic patients is increasing. Liver is a most common site
of progression from gastrointestinal, lung and breast cancer and in the setting
of oligometastatic patients, surgical resection is associated with increased
survival. Approximately 70-90% of liver metastases, however, are unresectable and
an effective and safe alternative therapeutic option is necessary for these
patients. The role of stereotactic body radiation therapy (SBRT) was investigated
in the treatment of oligometastatic patients with promising results, thanks to
the ability of this procedure to deliver a conformal high dose of radiation to
the target lesion and a minimal dose to surrounding critical tissues. This paper
was performed to review the current literature and to provide the practice
guidelines on the use of stereotactic body radiotherapy in the treatment of liver
metastases. We performed a literature search using Medical Subject Heading terms
"SBRT" and "liver metastases", considering a period of ten years.