Status epilepticus and refractory status epilepticus management
#MMPMID25727508
Abend NS
; Bearden D
; Helbig I
; McGuire J
; Narula S
; Panzer JA
; Topjian A
; Dlugos DJ
Semin Pediatr Neurol
2014[Dec]; 21
(4
): 263-74
PMID25727508
show ga
Status epilepticus (SE) describes persistent or recurring seizures without a
return to baseline mental status and is a common neurologic emergency. SE can
occur in the context of epilepsy or may be symptomatic of a wide range of
underlying etiologies. The clinician's aim is to rapidly institute care that
simultaneously stabilizes the patient medically, identifies and manages any
precipitant conditions, and terminates seizures. Seizure management involves
"emergent" treatment with benzodiazepines followed by "urgent" therapy with other
antiseizure medications. If seizures persist, then refractory SE is diagnosed and
management options include additional antiseizure medications or infusions of
midazolam or pentobarbital. This article reviews the management of pediatric SE
and refractory SE.
free
free
free
