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10.1016/j.cell.2015.10.026 http://scihub22266oqcxt.onion/10.1016/j.cell.2015.10.026 C4639323!4639323 !26544940     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26544940 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell 2015 ; 163 (4 ): 934-46 Nephropedia Template TP {{tp|p=26544940 |t=2015. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture |pdf=|usr=}}{{26544940 }} gab.com Text Stable Chromosome Condensation Revealed by Chromosome Conformation Capture JO: Cell http://www.kidney.de/pget.php?&tw=1&pmid=26544940 #FOAvip Chemical cross-linking and DNA sequencing have revealed regions of intra-chromosomal interaction, referred to as topologically associating domains (TADs), interspersed with regions of little or no interaction, in interphase nuclei. We find that TADs and the regions between them correspond with the bands and interbands of polytene chromosomes of Drosophila. We further establish the conservation of TADs between polytene and diploid cells of Drosophila. From direct measurements on light micrographs of polytene chromosomes, we then deduce the states of chromatin folding in the diploid cell nucleus. Two states of folding, fully extended fibers containing regulatory regions and promoters, and fibers condensed up to 10-fold containing coding regions of active genes, constitute the euchromatin of the nuclear interior. Chromatin fibers condensed up to 30-fold, containing coding regions of inactive genes, represent the heterochromatin of the nuclear periphery. A convergence of molecular analysis with direct observation thus reveals the architecture of interphase chromosomes. Twit Text FOAVip Stable Chromosome Condensation Revealed by Chromosome Conformation Capture ????Cell http://www.kidney.de/pget.php?&tw=1&pmid=26544940 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26544940 #FOAvip English Wikipedia <ref>{{Cite pmid|26544940 }}</ref> Stable Chromosome Condensation Revealed by Chromosome Conformation Capture #MMPMID26544940 Eagen KP ; Hartl TA ; Kornberg RD Cell 2015[Nov]; 163 (4 ): 934-46 PMID26544940 show ga Chemical cross-linking and DNA sequencing have revealed regions of intra-chromosomal interaction, referred to as topologically associating domains (TADs), interspersed with regions of little or no interaction, in interphase nuclei. We find that TADs and the regions between them correspond with the bands and interbands of polytene chromosomes of Drosophila. We further establish the conservation of TADs between polytene and diploid cells of Drosophila. From direct measurements on light micrographs of polytene chromosomes, we then deduce the states of chromatin folding in the diploid cell nucleus. Two states of folding, fully extended fibers containing regulatory regions and promoters, and fibers condensed up to 10-fold containing coding regions of active genes, constitute the euchromatin of the nuclear interior. Chromatin fibers condensed up to 30-fold, containing coding regions of inactive genes, represent the heterochromatin of the nuclear periphery. A convergence of molecular analysis with direct observation thus reveals the architecture of interphase chromosomes. |Animals [MESH] |Cell Nucleus/chemistry/genetics [MESH] |Chromosomal Puffs [MESH] |Diploidy [MESH] |Drosophila melanogaster/chemistry/cytology/*genetics/growth & development [MESH] |Genetic Techniques [MESH] |Larva/chemistry [MESH]Stable Chromosome Condensation Revealed by Chromosome Conformation Cap(epmc).pdf DeepDyve Pubget Overpricing