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10.2147/DDDT.S81944 http://scihub22266oqcxt.onion/10.2147/DDDT.S81944 C4662369!4662369 !26640371     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26640371 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Drug+Des+Devel+Ther 2015 ; 9 (ä): 6185-90 Nephropedia Template TP {{tp|p=26640371 |t=2015. Spotlight on tavaborole for the treatment of onychomycosis |pdf=|usr=}}{{26640371 }} gab.com Text Spotlight on tavaborole for the treatment of onychomycosis JO: Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=26640371 #FOAvip Onychomycosis is a fungal nail plate infection that has been increasing in prevalence. A variety of oral and topical anti-fungal agents are currently available but their use is limited by their adverse effect profile, drug-drug interactions, and limited efficacy. Therefore, there is a great need for newer anti-fungal agents. Tavaborole is one of these newer agents and was approved by the US Food and Drug Administration in July 2014 for the topical treatment of mild to moderate toenail onychomycosis. Tavaborole is a novel, boron-based anti-fungal agent with greater nail plate penetration than its predecessors, due to its smaller molecular weight. It has proven through several Phase II and III trials that it can be a safe and effective topical agent for the treatment of mild to moderate toenail onychomycosis without the need for debridement. In this paper, we review the landscape of topical and systemic treatment of onychomycosis, with particular attention to the pharmacokinetics, safety, and efficacy of topical tavaborole. Twit Text FOAVip Spotlight on tavaborole for the treatment of onychomycosis ????Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=26640371 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26640371 #FOAvip English Wikipedia <ref>{{Cite pmid|26640371 }}</ref> Spotlight on tavaborole for the treatment of onychomycosis #MMPMID26640371 Jinna S ; Finch J Drug Des Devel Ther 2015[]; 9 (ä): 6185-90 PMID26640371 show ga Onychomycosis is a fungal nail plate infection that has been increasing in prevalence. A variety of oral and topical anti-fungal agents are currently available but their use is limited by their adverse effect profile, drug-drug interactions, and limited efficacy. Therefore, there is a great need for newer anti-fungal agents. Tavaborole is one of these newer agents and was approved by the US Food and Drug Administration in July 2014 for the topical treatment of mild to moderate toenail onychomycosis. Tavaborole is a novel, boron-based anti-fungal agent with greater nail plate penetration than its predecessors, due to its smaller molecular weight. It has proven through several Phase II and III trials that it can be a safe and effective topical agent for the treatment of mild to moderate toenail onychomycosis without the need for debridement. In this paper, we review the landscape of topical and systemic treatment of onychomycosis, with particular attention to the pharmacokinetics, safety, and efficacy of topical tavaborole. |Administration, Topical [MESH] |Antifungal Agents/administration & dosage/adverse effects/*therapeutic use [MESH] |Boron Compounds/administration & dosage/adverse effects/*therapeutic use [MESH] |Bridged Bicyclo Compounds, Heterocyclic/administration & dosage/adverse effects/*therapeutic use [MESH] |Drug Approval [MESH] |Foot Dermatoses/drug therapy/microbiology [MESH] |Humans [MESH] |Onychomycosis/*drug therapy [MESH] |United States [MESH]Spotlight on tavaborole for the treatment of onychomycosis (epmc).pdf DeepDyve Pubget Overpricing