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2014 ; 6
(3
): 212-25
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Spore formation in Bacillus subtilis
#MMPMID24983526
Tan IS
; Ramamurthi KS
Environ Microbiol Rep
2014[Jun]; 6
(3
): 212-25
PMID24983526
show ga
Although prokaryotes ordinarily undergo binary fission to produce two identical
daughter cells, some are able to undergo alternative developmental pathways that
produce daughter cells of distinct cell morphology and fate. One such example is
a developmental programme called sporulation in the bacterium Bacillus subtilis,
which occurs under conditions of environmental stress. Sporulation has long been
used as a model system to help elucidate basic processes of developmental biology
including transcription regulation, intercellular signalling, membrane
remodelling, protein localization and cell fate determination. This review
highlights some of the recent work that has been done to further understand
prokaryotic cell differentiation during sporulation and its potential
applications.