Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1084/jem.145.1.76 http://scihub22266oqcxt.onion/10.1084/jem.145.1.76 C2180591!2180591 !830791     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\830791 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Exp+Med 1977 ; 145 (1 ): 76-85 Nephropedia Template TP {{tp|p=830791 |t=1977. Specific binding of soluble fibrin to macrophages |pdf=|usr=}}{{830791 }} gab.com Text Specific binding of soluble fibrin to macrophages JO: J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=830791 #FOAvip Guinea pig peritoneal macrophages were demonstrated to bind selectively soluble 125I-fibrin and fibrin/fibrinogen complexes as compared with fibrinogen, fibrinogen degradation products, and fibrin degradation products. Cellular uptake was considered to be surface receptor binding on the basis of removal of bound 125I-fibrin by trypsin and because uptake occurred in the presence of metabolic inhibitors. 125I-fibrin uptake could be blocked by nonradioactive fibrin but not by IgG or immune complexes. Binding was uneffected by prior treatment with plasmin or trypsin but was calcium dependent. Only limited reversibility of binding could be demonstrated after prolonged incubation. Scatchard plots permitted an estimate of the number of bound molecules. At saturation 6.92 X 10(6) 125I-fibrin molecules were bound per cell. Similar binding of fibrin was noted in polymorphonuclear leukocytes, but not lymphocytes or fibroblasts. Soluble fibrin binding may be a host defense mechanism whereby the reticuloendothelial system can remove fibrin from the blood before the development of microthrombi. Twit Text FOAVip Specific binding of soluble fibrin to macrophages ????J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=830791 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=830791 #FOAvip English Wikipedia <ref>{{Cite pmid|830791 }}</ref> Specific binding of soluble fibrin to macrophages #MMPMID830791 Sherman LA ; Lee J J Exp Med 1977[Jan]; 145 (1 ): 76-85 PMID830791 show ga Guinea pig peritoneal macrophages were demonstrated to bind selectively soluble 125I-fibrin and fibrin/fibrinogen complexes as compared with fibrinogen, fibrinogen degradation products, and fibrin degradation products. Cellular uptake was considered to be surface receptor binding on the basis of removal of bound 125I-fibrin by trypsin and because uptake occurred in the presence of metabolic inhibitors. 125I-fibrin uptake could be blocked by nonradioactive fibrin but not by IgG or immune complexes. Binding was uneffected by prior treatment with plasmin or trypsin but was calcium dependent. Only limited reversibility of binding could be demonstrated after prolonged incubation. Scatchard plots permitted an estimate of the number of bound molecules. At saturation 6.92 X 10(6) 125I-fibrin molecules were bound per cell. Similar binding of fibrin was noted in polymorphonuclear leukocytes, but not lymphocytes or fibroblasts. Soluble fibrin binding may be a host defense mechanism whereby the reticuloendothelial system can remove fibrin from the blood before the development of microthrombi. |Animals [MESH] |Antigen-Antibody Complex [MESH] |Ascitic Fluid/cytology [MESH] |Binding Sites [MESH] |Blood Cells/metabolism [MESH] |Calcium/pharmacology [MESH] |Fibrin Fibrinogen Degradation Products/*metabolism [MESH] |Fibrin/*metabolism [MESH] |Fibrinogen/*metabolism [MESH] |Guinea Pigs [MESH] |Immunoglobulin G/metabolism [MESH] |Kinetics [MESH] |Macrophages/*metabolism [MESH] |Magnesium/pharmacology [MESH] |Membrane Proteins/metabolism [MESH] |Neutrophils/metabolism [MESH]Specific binding of soluble fibrin to macrophages (epmc).pdf DeepDyve Pubget Overpricing