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2014 ; 2014
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Sore throat
#MMPMID24589314
Kenealy T
BMJ Clin Evid
2014[Mar]; 2014
(ä): ä PMID24589314
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INTRODUCTION: About 10% of people present to primary healthcare services with
sore throat each year. The causative organisms of sore throat may be bacteria
(most commonly Streptococcus) or viruses (typically rhinovirus), although it is
difficult to distinguish bacterial from viral infections clinically. METHODS AND
OUTCOMES: We conducted a systematic review and aimed to answer the following
clinical question: What are the effects of interventions to reduce symptoms of
acute infective sore throat? We searched Medline, Embase, The Cochrane Library,
and other important databases up to September 2013 (Clinical Evidence reviews are
updated periodically; please check our website for the most up-to-date version of
this review). We included harms alerts from relevant organisations such as the US
Food and Drug Administration (FDA) and the UK Medicines and Healthcare products
Regulatory Agency (MHRA). RESULTS: We found 6 studies that met our inclusion
criteria. We performed a GRADE evaluation of the quality of evidence for
interventions. CONCLUSIONS: In this systematic review, we present information
relating to the effectiveness and safety of the following interventions:
antibiotics, corticosteroids, non-steroidal anti-inflammatory drugs, and
paracetamol.
|Acetaminophen/therapeutic use
[MESH]
|Adrenal Cortex Hormones/*therapeutic use
[MESH]
|Anti-Bacterial Agents/*therapeutic use
[MESH]
|Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use
[MESH]