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2014 ; 202
(6
): 1196-206
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Solid renal masses: what the numbers tell us
#MMPMID24848816
Kang SK
; Huang WC
; Pandharipande PV
; Chandarana H
AJR Am J Roentgenol
2014[Jun]; 202
(6
): 1196-206
PMID24848816
show ga
OBJECTIVE: Solid renal masses are most often incidentally detected at imaging as
small (? 4 cm) localized lesions. These lesions comprise a wide spectrum of
benign and malignant histologic subtypes, but are largely treated with surgical
resection given the limited ability of imaging to differentiate among them with
consistency and high accuracy. Numerous studies have thus examined the ability of
CT and MRI techniques to separate benign lesions from malignancies and to predict
renal cancer histologic grade and subtype. This article synthesizes the evidence
regarding renal mass characterization at CT and MRI, provides diagnostic
algorithms for evidence-based practice, and highlights areas of further research
needed to drive imaging-based management of renal masses. CONCLUSION: Despite
extensive study of morphologic and quantitative criteria at conventional imaging,
no CT or MRI techniques can reliably distinguish solid benign tumors, such as
oncocytoma and lipid-poor angiomyolipoma, from malignant renal tumors. Larger
studies are required to validate recently developed techniques, such as
diffusion-weighted imaging. Evidence-based practice includes MRI to assess renal
lesions in situations where CT is limited and to help guide management in
patients who are considered borderline surgical candidates.