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10.4161/23723556.2014.977160

http://scihub22266oqcxt.onion/10.4161/23723556.2014.977160
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C4905251!4905251 !27308410
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suck abstract from ncbi


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pmid27308410
      Mol+Cell+Oncol 2015 ; 2 (1 ): e977160
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  • Small molecule targeting miR-34a for cancer therapy #MMPMID27308410
  • Xiao Z ; Chen Y
  • Mol Cell Oncol 2015[Jan]; 2 (1 ): e977160 PMID27308410 show ga
  • miR-34a functions as a tumor suppressor in many cancers. In a recent issue of Cancer Research, we describe a small molecule, Rubone, with strong anticancer activity. Rubone selectively restored miR-34a expression in hepatocellular carcinoma cells in which miR-34a was silenced. Restoration of miR-34a by Rubone represents a promising therapeutic approach against cancer.
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