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10.1111/j.1582-4934.2010.01080.x http://scihub22266oqcxt.onion/10.1111/j.1582-4934.2010.01080.x C3822738!3822738 !20455998     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20455998 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\20455998 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Cell+Mol+Med 2010 ; 14 (5 ): 1037-43 Nephropedia Template TP {{tp|p=20455998 |t=2010. Small artery structure and function in hypertension |pdf=|usr=}}{{20455998 }} gab.com Text Small artery structure and function in hypertension JO: J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=20455998 #FOAvip It has been known for some considerable time that sustained hypertension changes the circulatory architecture both in the heart and blood vessels. The histopathological alterations are of considerable interest because once they have developed they appear to carry an adverse prognostic risk. In the heart it is apparent that there is hypertrophy. This extends also to the large- and medium-sized blood vessels but at the level of the smaller arteries that contribute to vascular resistance, this is not the case: it is clear that the physiological response to higher pressures is a change in the positional conformation of the pre-existing tissue constituents and as a result of this the lumen is narrowed. This brief review looks at our knowledge in this area and attempts to clarify our understanding of how hypertension brings these about and what happens when these homeostatic mechanisms break down. From a therapeutic perspective it appears imperative to control blood pressure in an attempt to reverse or prevent such alterations to cardiovascular structure. Our knowledge is fast expanding in this field and it is only to be anticipated that as detection methodology improves everyday practice will alter as we profile our patients in terms of structural alterations in the ventricle and blood vessels. Twit Text FOAVip Small artery structure and function in hypertension ????J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=20455998 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20455998 #FOAvip English Wikipedia <ref>{{Cite pmid|20455998 }}</ref> Small artery structure and function in hypertension #MMPMID20455998 Heagerty AM ; Heerkens EH ; Izzard AS J Cell Mol Med 2010[May]; 14 (5 ): 1037-43 PMID20455998 show ga It has been known for some considerable time that sustained hypertension changes the circulatory architecture both in the heart and blood vessels. The histopathological alterations are of considerable interest because once they have developed they appear to carry an adverse prognostic risk. In the heart it is apparent that there is hypertrophy. This extends also to the large- and medium-sized blood vessels but at the level of the smaller arteries that contribute to vascular resistance, this is not the case: it is clear that the physiological response to higher pressures is a change in the positional conformation of the pre-existing tissue constituents and as a result of this the lumen is narrowed. This brief review looks at our knowledge in this area and attempts to clarify our understanding of how hypertension brings these about and what happens when these homeostatic mechanisms break down. From a therapeutic perspective it appears imperative to control blood pressure in an attempt to reverse or prevent such alterations to cardiovascular structure. Our knowledge is fast expanding in this field and it is only to be anticipated that as detection methodology improves everyday practice will alter as we profile our patients in terms of structural alterations in the ventricle and blood vessels. |Arteries/*pathology/*physiopathology [MESH] |Blood Circulation/physiology [MESH] |Humans [MESH] |Hypertension/*physiopathology [MESH]Small artery structure and function in hypertension (epmc).pdf DeepDyve Pubget Overpricing