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10.3390/ijms18050912 http://scihub22266oqcxt.onion/10.3390/ijms18050912 C5454825!5454825 !28445427     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28445427 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28445427 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2017 ; 18 (5 ): ä Nephropedia Template TP {{tp|p=28445427 |t=2017. Small RNA Pathways That Protect the Somatic Genome |pdf=|usr=}}{{28445427 }} gab.com Text Small RNA Pathways That Protect the Somatic Genome JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28445427 #FOAvip Transposable elements (TEs) are DNA elements that can change their position within the genome, with the potential to create mutations and destabilize the genome. As such, special molecular systems have been adopted in animals to control TE activity in order to protect the genome. PIWI proteins, in collaboration with PIWI-interacting RNAs (piRNAs), are well known to play a critical role in silencing germline TEs. Although initially thought to be germline-specific, the role of PIWI-piRNA pathways in controlling TEs in somatic cells has recently begun to be explored in various organisms, together with the role of endogenous small interfering RNAs (endo-siRNAs). This review summarizes recent results suggesting that these small RNA pathways have been critically implicated in the silencing of somatic TEs underlying various physiological traits, with a special focus on the Drosophila model organism. Twit Text FOAVip Small RNA Pathways That Protect the Somatic Genome ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28445427 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28445427 #FOAvip English Wikipedia <ref>{{Cite pmid|28445427 }}</ref> Small RNA Pathways That Protect the Somatic Genome #MMPMID28445427 Hyun S Int J Mol Sci 2017[Apr]; 18 (5 ): ä PMID28445427 show ga Transposable elements (TEs) are DNA elements that can change their position within the genome, with the potential to create mutations and destabilize the genome. As such, special molecular systems have been adopted in animals to control TE activity in order to protect the genome. PIWI proteins, in collaboration with PIWI-interacting RNAs (piRNAs), are well known to play a critical role in silencing germline TEs. Although initially thought to be germline-specific, the role of PIWI-piRNA pathways in controlling TEs in somatic cells has recently begun to be explored in various organisms, together with the role of endogenous small interfering RNAs (endo-siRNAs). This review summarizes recent results suggesting that these small RNA pathways have been critically implicated in the silencing of somatic TEs underlying various physiological traits, with a special focus on the Drosophila model organism. |*Genome [MESH] |Animals [MESH] |DNA Transposable Elements/genetics [MESH] |Drosophila/genetics [MESH] |RNA Interference [MESH] |RNA, Small Interfering/antagonists & inhibitors/genetics/metabolism [MESH]Small RNA Pathways That Protect the Somatic Genome (epmc).pdf DeepDyve Pubget Overpricing