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10.1101/cshperspect.a016378 http://scihub22266oqcxt.onion/10.1101/cshperspect.a016378 C4382741!4382741 !25502514     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25502514 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cold+Spring+Harb+Perspect+Biol 2014 ; 7 (4 ): a016378 Nephropedia Template TP {{tp|p=25502514 |t=2014. Sinusoidal immunity: macrophages at the lymphohematopoietic interface |pdf=|usr=}}{{25502514 }} gab.com Text Sinusoidal immunity: macrophages at the lymphohematopoietic interface JO: Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=25502514 #FOAvip Macrophages are widely distributed throughout the body, performing vital homeostatic and defense functions after local and systemic perturbation within tissues. In concert with closely related dendritic cells and other myeloid and lymphoid cells, which mediate the innate and adaptive immune response, macrophages determine the outcome of the inflammatory and repair processes that accompany sterile and infectious injury and microbial invasion. This article will describe and compare the role of specialized macrophage populations at two critical interfaces between the resident host lymphohematopoietic system and circulating blood and lymph, the carriers of cells, humoral components, microorganisms, and their products. Sinusoidal macrophages in the marginal zone of the spleen and subcapsular sinus and medulla of secondary lymph nodes contribute to the innate and adaptive responses of the host in health and disease. Although historically recognized as major constituents of the reticuloendothelial system, it has only recently become apparent that these specialized macrophages in close proximity to B and T lymphocytes play an indispensable role in recognition and responses to exogenous and endogenous ligands, thus shaping the nature and quality of immunity and inflammation. We review current understanding of these macrophages and identify gaps in our knowledge for further investigation. Twit Text FOAVip Sinusoidal immunity: macrophages at the lymphohematopoietic interface ????Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=25502514 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25502514 #FOAvip English Wikipedia <ref>{{Cite pmid|25502514 }}</ref> Sinusoidal immunity: macrophages at the lymphohematopoietic interface #MMPMID25502514 Gordon S ; Plüddemann A ; Mukhopadhyay S Cold Spring Harb Perspect Biol 2014[Dec]; 7 (4 ): a016378 PMID25502514 show ga Macrophages are widely distributed throughout the body, performing vital homeostatic and defense functions after local and systemic perturbation within tissues. In concert with closely related dendritic cells and other myeloid and lymphoid cells, which mediate the innate and adaptive immune response, macrophages determine the outcome of the inflammatory and repair processes that accompany sterile and infectious injury and microbial invasion. This article will describe and compare the role of specialized macrophage populations at two critical interfaces between the resident host lymphohematopoietic system and circulating blood and lymph, the carriers of cells, humoral components, microorganisms, and their products. Sinusoidal macrophages in the marginal zone of the spleen and subcapsular sinus and medulla of secondary lymph nodes contribute to the innate and adaptive responses of the host in health and disease. Although historically recognized as major constituents of the reticuloendothelial system, it has only recently become apparent that these specialized macrophages in close proximity to B and T lymphocytes play an indispensable role in recognition and responses to exogenous and endogenous ligands, thus shaping the nature and quality of immunity and inflammation. We review current understanding of these macrophages and identify gaps in our knowledge for further investigation. |Animals [MESH] |Cell Adhesion Molecules/metabolism [MESH] |Humans [MESH] |Lectins, C-Type/metabolism [MESH] |Lymph Nodes/anatomy & histology/*immunology [MESH] |Macrophages/cytology/*physiology [MESH] |Mannose Receptor [MESH] |Mannose-Binding Lectins/metabolism [MESH] |Phenotype [MESH] |Receptors, Cell Surface/metabolism [MESH] |Receptors, Immunologic/metabolism [MESH]Sinusoidal immunity: macrophages at the lymphohematopoietic interface (epmc).pdf DeepDyve Pubget Overpricing