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Significance of penile hypersensitivity in premature ejaculation
#MMPMID28874780
Guo L
; Liu Y
; Wang X
; Yuan M
; Yu Y
; Zhang X
; Zhao S
Sci Rep
2017[Sep]; 7
(1
): 10441
PMID28874780
show ga
To assess the correlation between penile hypersensitivity and premature
ejaculation (PE), a total of 420 consecutive subjects attending our andrologic
clinic for suspected PE were enrolled. The entire cohort was asked to complete
the self-report intravaginal ejaculation latency time (IELT) by stopwatch.
According to the IELT, the subjects were classified into 3 groups. Vibratory
thresholds were recorded at the glans penis and penile shaft using a
biothesiometer. We found that vibratory thresholds in the glans penis and penile
shaft were significantly lower in both mild and severe PE group than in the
control group (3.81?±?0.57 and 3.54?±?0.43 vs 4.73?±?0.77 for glans penis
p?=?0.000; 3.64?±?0.52 and 3.37?±?0.50 vs 4.62?±?0.69 for penile shaft
p?=?0.002). The vibratory threshold decreased as the disease aggravated. In the
mild and severe PE groups, a significant positive correlation was detected
between the mean values of IELT and the vibratory thresholds. Furthermore, in the
receiver operating characteristics curve analysis, the area under the curve of
the glans penis and penile shaft vibratory thresholds predicting severe PE were
0.852 and 0.893 respectively. Our study established a dose-dependent association
between penile vibratory threshold and PE. Therefore, the vibratory threshold can
serve as a potential marker for predicting the severity of PE.
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