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2015 ; 4
(ä): 8
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Short Course in the Microbiome
#MMPMID28936244
Falana K
; Knight R
; Martin CR
; Goldszmid R
; Greathouse KL
; Gere J
; Young H
; Kuo WP
J Circ Biomark
2015[Jan]; 4
(ä): 8
PMID28936244
show ga
Over the past decade, it has become evident that the microbiome is an important
environmental factor that affects many physiological processes, such as cell
proliferation and differentiation, behaviour, immune function and metabolism.
More importantly, it may contribute to a wide variety of diseases, including
cancer, inflammatory diseases, metabolic diseases and responses to pathogens. We
expect that international, integrative and interdisciplinary translational
research teams, along with the emergence of FDA-approved platforms, will set the
framework for microbiome-based therapeutics and diagnostics. We recognize that
the microbiome ecosystem offers new promise for personalized/precision medicine
and targeted treatment for a variety of diseases. The short course was held as a
four-session webinar series in April 2015, taught by pioneers and experts in the
microbiome ecosystem, covering a broad range of topics from the healthy
microbiome to the effects of an altered microbiome from neonates to adults and
the long term effects as it is related to disease, from asthma to cancer. We have
learned to appreciate how beneficial our microbes are in breaking down our food,
fighting off infections and nurturing our immune system, and this information
provides us with ideas as to how we can manipulate our microbiome to prevent
certain diseases. However, given the variety of applications, there are
scientific challenges, though there are very promising areas in reference to the
clinical benefits of understanding more about our microbiome, whether in our gut
or on our skin: the outlook is bright. A summary of the short course is presented
as a meeting dispatch.