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2015 ; 50
(ä): 1.27.1-1.27.10
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Searching and Navigating UniProt Databases
#MMPMID26088053
Pundir S
; Magrane M
; Martin MJ
; O'Donovan C
Curr Protoc Bioinformatics
2015[Jun]; 50
(ä): 1.27.1-1.27.10
PMID26088053
show ga
The Universal Protein Resource (UniProt) is a comprehensive resource for protein
sequence and annotation data. The UniProt Web site receives ?400,000 unique
visitors per month and is the primary means to access UniProt. It provides ten
searchable datasets and three main tools. The key UniProt datasets are the
UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), the
UniProt Archive (UniParc), and protein sets for completely sequenced genomes
(Proteomes). Other supporting datasets include information about proteins that is
present in UniProtKB protein entries such as literature citations, taxonomy, and
subcellular locations, among others. This paper focuses on how to use UniProt
datasets. The basic protocol describes navigation and searching mechanisms for
the UniProt datasets, while two alternative protocols build on the basic protocol
to describe advanced search and query building.