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10.1016/j.bone.2016.11.024 http://scihub22266oqcxt.onion/10.1016/j.bone.2016.11.024 C5328839!5328839 !27888056     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27888056 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Bone 2017 ; 96 (ä): 45-50 Nephropedia Template TP {{tp|p=27888056 |t=2017. Sclerostin expression and functions beyond the osteocyte |pdf=|usr=}}{{27888056 }} gab.com Text Sclerostin expression and functions beyond the osteocyte JO: Bone http://www.kidney.de/pget.php?&tw=1&pmid=27888056 #FOAvip Sclerostin, the product of the SOST gene, is a secreted inhibitor of Wnt signaling that is produced by osteocytes to regulate bone formation. While it is often considered an osteocyte-specific protein, SOST expression has been reported in numerous other cell types, including hypertrophic chondrocytes and cementocytes. Of interest, SOST/sclerostin expression is altered in certain pathogenic conditions, including osteoarthritis and rheumatic joint disease, and it is unclear whether sclerostin plays a protective role or whether sclerostin may mediate disease pathogenesis. Therefore, as anti-sclerostin antibodies are being developed for the treatment of osteoporosis, it is important to understand the functions of sclerostin beyond the regulation of bone formation. Twit Text FOAVip Sclerostin expression and functions beyond the osteocyte ????Bone http://www.kidney.de/pget.php?&tw=1&pmid=27888056 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27888056 #FOAvip English Wikipedia <ref>{{Cite pmid|27888056 }}</ref> Sclerostin expression and functions beyond the osteocyte #MMPMID27888056 Weivoda MM ; Youssef SJ ; Oursler MJ Bone 2017[Mar]; 96 (ä): 45-50 PMID27888056 show ga Sclerostin, the product of the SOST gene, is a secreted inhibitor of Wnt signaling that is produced by osteocytes to regulate bone formation. While it is often considered an osteocyte-specific protein, SOST expression has been reported in numerous other cell types, including hypertrophic chondrocytes and cementocytes. Of interest, SOST/sclerostin expression is altered in certain pathogenic conditions, including osteoarthritis and rheumatic joint disease, and it is unclear whether sclerostin plays a protective role or whether sclerostin may mediate disease pathogenesis. Therefore, as anti-sclerostin antibodies are being developed for the treatment of osteoporosis, it is important to understand the functions of sclerostin beyond the regulation of bone formation. |Animals [MESH] |Bone Morphogenetic Proteins/*metabolism [MESH] |Disease [MESH] |Humans [MESH] |Organ Specificity [MESH]Sclerostin expression and functions beyond the osteocyte (epmc).pdf DeepDyve Pubget Overpricing