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10.1016/bs.pmbts.2015.05.005

http://scihub22266oqcxt.onion/10.1016/bs.pmbts.2015.05.005
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suck abstract from ncbi


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pmid26310158
      Prog+Mol+Biol+Transl+Sci 2015 ; 134 (ä): 241-8
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  • Scleral Mechanisms Underlying Ocular Growth and Myopia #MMPMID26310158
  • Metlapally R ; Wildsoet CF
  • Prog Mol Biol Transl Sci 2015[]; 134 (ä): 241-8 PMID26310158 show ga
  • In the regulation of ocular growth, scleral events critically determine eye size and thus the refractive status of the eye. Increased scleral matrix remodeling can lead to exaggerated eye growth causing myopia and additionally increased risk of ocular pathological complications. Thus, therapies targeting these changes in sclera hold potential to limit such complications since sclera represents a relatively safe and accessible drug target. Understanding the scleral molecular mechanisms underlying ocular growth is essential to identifying plausible therapeutic targets in the sclera. This section provides a brief update on molecular studies that pertain to the sclera in the context of ocular growth regulation and myopia.
  • |Biomechanical Phenomena [MESH]
  • |Humans [MESH]
  • |Models, Biological [MESH]
  • |Myopia/genetics/*pathology/physiopathology/therapy [MESH]


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