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2014 ; 16
(7
): 452
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Schizotypal personality disorder: a current review
#MMPMID24828284
Rosell DR
; Futterman SE
; McMaster A
; Siever LJ
Curr Psychiatry Rep
2014[Jul]; 16
(7
): 452
PMID24828284
show ga
The study of schizotypal personality disorder (SPD) is important clinically, as
it is understudied, challenging to treat, often under-recognized or misdiagnosed,
and associated with significant functional impairment. SPD also represents an
intermediate schizophrenia-spectrum phenotype, and therefore, can provide a
better understanding of the genetics, pathogenesis, and treatment of related
psychotic illnesses. In this review we discuss recent findings of SPD related to
epidemiology and functional impairment, heritability and genetics, working memory
and cognitive impairments, social-affective disturbances, and neurobiology.
Additionally, we examine the challenges associated with treating patients with
SPD, as well as clinical recommendations. Finally, we address future directions
and areas in need of further exploration.