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2013 ; 2013
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Sarcoidosis of the pancreas mimicking adenocarcinoma
#MMPMID23784760
Mayne AI
; Ahmad J
; Loughrey M
; Taylor MA
BMJ Case Rep
2013[Jun]; 2013
(ä): ä PMID23784760
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Primary sarcoidosis of the pancreas is extremely rare. Clinical presentation is
often identical to that of pancreatic adenocarcinoma. Preoperative diagnosis of
primary pancreatic sarcoidosis is always challenging. We present a 52-year-old
man who developed weight loss and obstructive jaundice. Abdomino-pelvic CT scan
showed a mass in the pancreatic head. After hepatopancreaticobiliary MDT
discussion, a Whipple's procedure was attempted but the mass was deemed
unresectable due to invasion of the superior mesenteric vein. Upon completion of
palliative chemotherapy, repeat imaging showed significant mass shrinkage. A
reattempt Whipple's procedure was successfully undertaken. Histology showed
changes of chronic pancreatitis and peripancreatic granulomatous inflammation
with no evidence of malignancy and a diagnosis of sarcoidosis was made. Owing to
the devastating nature of pancreatic adenocarcinoma, any mass in the pancreas
must be thoroughly investigated before a definitive diagnosis is made.
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