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10.1111/mmi.12739 http://scihub22266oqcxt.onion/10.1111/mmi.12739 C4160465!4160465 !25081030     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25081030 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25081030 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Microbiol 2014 ; 93 (6 ): 1314-26 Nephropedia Template TP {{tp|p=25081030 |t=2014. Salmonella acquires ferrous iron from haemophagocytic macrophages |pdf=|usr=}}{{25081030 }} gab.com Text Salmonella acquires ferrous iron from haemophagocytic macrophages JO: Mol Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25081030 #FOAvip Bacteria harbour both ferrous and ferric iron transporters. We now report that infection of macrophages and mice with a Salmonella enterica?Typhimurium strain containing an inactivated feoB-encoded ferrous iron transporter results in increased bacterial replication, compared to infection with wild type. Inactivation of other cation transporters, SitABCD or MntH, did not increase bacterial replication. The feoB mutant strain does not have an intrinsically faster growth rate. Instead, increased replication correlated with increased expression in macrophages of the fepB-encoded bacterial ferric iron transporter and also required siderophores, which capture ferric iron. Co-infection of mice with wild type and a feoB mutant strain yielded a different outcome: FeoB is clearly required for tissue colonization. In co-infected primary mouse macrophages, FeoB is required for S.?Typhimurium replication if the macrophages were IFN? treated and contain phagocytosed erythrocytes, a model for haemophagocytosis. Haemophagocytes are macrophages that have engulfed erythrocytes and/or leucocytes and can harbour Salmonella in mice. These observations suggest that Salmonella acquires ferrous iron from haemophagocytic macrophages. Twit Text FOAVip Salmonella acquires ferrous iron from haemophagocytic macrophages ????Mol Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25081030 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25081030 #FOAvip English Wikipedia <ref>{{Cite pmid|25081030 }}</ref> Salmonella acquires ferrous iron from haemophagocytic macrophages #MMPMID25081030 Nagy TA ; Moreland SM ; Detweiler CS Mol Microbiol 2014[Sep]; 93 (6 ): 1314-26 PMID25081030 show ga Bacteria harbour both ferrous and ferric iron transporters. We now report that infection of macrophages and mice with a Salmonella enterica?Typhimurium strain containing an inactivated feoB-encoded ferrous iron transporter results in increased bacterial replication, compared to infection with wild type. Inactivation of other cation transporters, SitABCD or MntH, did not increase bacterial replication. The feoB mutant strain does not have an intrinsically faster growth rate. Instead, increased replication correlated with increased expression in macrophages of the fepB-encoded bacterial ferric iron transporter and also required siderophores, which capture ferric iron. Co-infection of mice with wild type and a feoB mutant strain yielded a different outcome: FeoB is clearly required for tissue colonization. In co-infected primary mouse macrophages, FeoB is required for S.?Typhimurium replication if the macrophages were IFN? treated and contain phagocytosed erythrocytes, a model for haemophagocytosis. Haemophagocytes are macrophages that have engulfed erythrocytes and/or leucocytes and can harbour Salmonella in mice. These observations suggest that Salmonella acquires ferrous iron from haemophagocytic macrophages. |Animals [MESH] |Bacterial Proteins/genetics/*metabolism [MESH] |Cation Transport Proteins/genetics/*metabolism [MESH] |Interferon-gamma/pharmacology [MESH] |Iron/*metabolism [MESH] |Liver/microbiology [MESH] |Macrophages/drug effects/*microbiology [MESH] |Mice [MESH] |Mutation [MESH] |Salmonella Infections, Animal/*microbiology [MESH] |Salmonella typhimurium/*growth & development/pathogenicity [MESH] |Siderophores/metabolism [MESH] |Spleen/microbiology [MESH]Salmonella acquires ferrous iron from haemophagocytic macrophages (epmc).pdf DeepDyve Pubget Overpricing