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10.4161/19491034.2014.990857 http://scihub22266oqcxt.onion/10.4161/19491034.2014.990857 C4615189!4615189!25425085     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25425085&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25425085.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nucleus 2015 ; 6 (1): 2-7 Nephropedia Template TP {{tp|p=25425085|t=2015. SUN proteins and nuclear envelope spacing |pdf=|usr=}}{{25425085}} gab.com Text SUN proteins and nuclear envelope spacing JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=25425085 #FOAvip The nuclear envelope consists of 2 membranes separated by 30?50 nm, but how the 2 membranes are evenly spaced has been an open question in the field. Nuclear envelope bridges composed of inner nuclear membrane SUN proteins and outer nuclear membrane KASH proteins have been proposed to set and regulate nuclear envelope spacing. We tested this hypothesis directly by examining nuclear envelope spacing in Caenorhabditis elegans animals lacking UNC-84, the sole somatic SUN protein. SUN/KASH bridges are not required to maintain even nuclear envelope spacing in most tissues. However, UNC-84 is required for even spacing in body wall muscle nuclei. Shortening UNC-84 by 300 amino acids did not narrow the nuclear envelope space. While SUN proteins may play a role in maintaining nuclear envelope spacing in cells experiencing forces, our data suggest they are dispensable in most cells. Twit Text FOAVip SUN proteins and nuclear envelope spacing ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=25425085 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25425085 #FOAvip English Wikipedia <ref>{{Cite pmid|25425085}}</ref> SUN proteins and nuclear envelope spacing #MMPMID25425085 Cain NE; Starr DA Nucleus 2015[]; 6 (1): 2-7 PMID25425085show ga The nuclear envelope consists of 2 membranes separated by 30?50 nm, but how the 2 membranes are evenly spaced has been an open question in the field. Nuclear envelope bridges composed of inner nuclear membrane SUN proteins and outer nuclear membrane KASH proteins have been proposed to set and regulate nuclear envelope spacing. We tested this hypothesis directly by examining nuclear envelope spacing in Caenorhabditis elegans animals lacking UNC-84, the sole somatic SUN protein. SUN/KASH bridges are not required to maintain even nuclear envelope spacing in most tissues. However, UNC-84 is required for even spacing in body wall muscle nuclei. Shortening UNC-84 by 300 amino acids did not narrow the nuclear envelope space. While SUN proteins may play a role in maintaining nuclear envelope spacing in cells experiencing forces, our data suggest they are dispensable in most cells. äSUN proteins and nuclear envelope spacing (epmc).pdf DeepDyve Pubget Overpricing