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10.1007/978-1-4939-6433-8_6 http://scihub22266oqcxt.onion/10.1007/978-1-4939-6433-8_6 C5353976!5353976 !27665594     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27665594 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Methods+Mol+Biol 2016 ; 1490 (ä): 73-82 Nephropedia Template TP {{tp|p=27665594 |t=2016. STarMir Tools for Prediction of microRNA Binding Sites |pdf=|usr=}}{{27665594 }} gab.com Text STarMir Tools for Prediction of microRNA Binding Sites JO: Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27665594 #FOAvip MicroRNAs (miRNAs) are a class of endogenous short noncoding RNAs that regulate gene expression by targeting messenger RNAs (mRNAs), which results in translational repression and/or mRNA degradation. As regulatory molecules, miRNAs are involved in many mammalian biological processes and also in the manifestation of certain human diseases. As miRNAs play central role in the regulation of gene expression, understanding miRNA-binding patterns is essential to gain an insight of miRNA mediated gene regulation and also holds promise for therapeutic applications. Computational prediction of miRNA binding sites on target mRNAs facilitates experimental investigation of miRNA functions. This chapter provides protocols for using the STarMir web server for improved predictions of miRNA binding sites on a target mRNA. As an application module of the Sfold RNA package, the current version of STarMir is an implementation of logistic prediction models developed with high-throughput miRNA binding data from cross-linking immunoprecipitation (CLIP) studies. The models incorporated comprehensive thermodynamic, structural, and sequence features, and were found to make improved predictions of both seed and seedless sites, in comparison to the established algorithms (Liu et al., Nucleic Acids Res 41:e138, 2013). Their broad applicability was indicated by their good performance in cross-species validation. STarMir is freely available at http://sfold.wadsworth.org/starmir.html . Twit Text FOAVip STarMir Tools for Prediction of microRNA Binding Sites ????Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27665594 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27665594 #FOAvip English Wikipedia <ref>{{Cite pmid|27665594 }}</ref> STarMir Tools for Prediction of microRNA Binding Sites #MMPMID27665594 Kanoria S ; Rennie W ; Liu C ; Carmack CS ; Lu J ; Ding Y Methods Mol Biol 2016[]; 1490 (ä): 73-82 PMID27665594 show ga MicroRNAs (miRNAs) are a class of endogenous short noncoding RNAs that regulate gene expression by targeting messenger RNAs (mRNAs), which results in translational repression and/or mRNA degradation. As regulatory molecules, miRNAs are involved in many mammalian biological processes and also in the manifestation of certain human diseases. As miRNAs play central role in the regulation of gene expression, understanding miRNA-binding patterns is essential to gain an insight of miRNA mediated gene regulation and also holds promise for therapeutic applications. Computational prediction of miRNA binding sites on target mRNAs facilitates experimental investigation of miRNA functions. This chapter provides protocols for using the STarMir web server for improved predictions of miRNA binding sites on a target mRNA. As an application module of the Sfold RNA package, the current version of STarMir is an implementation of logistic prediction models developed with high-throughput miRNA binding data from cross-linking immunoprecipitation (CLIP) studies. The models incorporated comprehensive thermodynamic, structural, and sequence features, and were found to make improved predictions of both seed and seedless sites, in comparison to the established algorithms (Liu et al., Nucleic Acids Res 41:e138, 2013). Their broad applicability was indicated by their good performance in cross-species validation. STarMir is freely available at http://sfold.wadsworth.org/starmir.html . |*Base Pairing [MESH] |*Binding Sites [MESH] |*Software [MESH] |Computational Biology/methods [MESH] |MicroRNAs/*chemistry/genetics [MESH] |Nucleic Acid Conformation [MESH] |RNA Folding [MESH] |RNA, Messenger/*chemistry/genetics [MESH] |User-Computer Interface [MESH]STarMir Tools for Prediction of microRNA Binding Sites (epmc).pdf DeepDyve Pubget Overpricing