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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Transl+Oncol
2015 ; 17
(12
): 1036-42
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SEOM guidelines for cervical cancer
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Oaknin A
; Rubio MJ
; Redondo A
; De Juan A
; Cueva Bañuelos JF
; Gil-Martin M
; Ortega E
; Garcia-Arias A
; Gonzalez-Martin A
; Bover I
Clin Transl Oncol
2015[Dec]; 17
(12
): 1036-42
PMID26650487
show ga
Cervical cancer (CC) is the second most common cancer worldwide, strongly linked
to high-risk human papilloma virus infection. Although screening programs have
led to a relevant reduction in the incidence and mortality due to CC in developed
countries, it is still an important cause of mortality in undeveloped countries.
Clinical stage is still the most relevant prognostic factor. In early stages, the
primary treatment is surgery or radiotherapy, whereas concomitant
chemo-radiotherapy is the conventional approach in locally advanced stages. In
the setting of recurrent or metastatic CC, for the first time ever, the
combination of chemotherapy plus bevacizumab prolongs the overall survival beyond
12 months. Therefore, this regimen is considered by most of the oncologist a new
standard of care for metastatic/recurrent CC.