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2017 ; 7
(ä): 205
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Roles of LncRNAs in Viral Infections
#MMPMID28603696
Liu W
; Ding C
Front Cell Infect Microbiol
2017[]; 7
(ä): 205
PMID28603696
show ga
Many proteins and signaling pathways participate in anti-viral host responses.
Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200
nucleotides in length, have been recently described as critical regulators in
viral infections. Accumulating research indicates that lncRNAs are important in
the development and progression of infectious diseases. LncRNAs are not only
involved in anti-viral responses, but in many different virus-host interactions,
some of which may be beneficial to the virus. Here we review the current
knowledge regarding host and viral lncRNAs and their roles in viral infections.
In addition, the potential of using lncRNAs as diagnostic biomarkers is
discussed.