Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.4103/0019-5154.182434 http://scihub22266oqcxt.onion/10.4103/0019-5154.182434 C4885183!4885183 !27293251     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27293251 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Indian+J+Dermatol 2016 ; 61 (3 ): 301-7 Nephropedia Template TP {{tp|p=27293251 |t=2016. Role of Osteopontin in Psoriasis: An Immunohistochemical Study |pdf=|usr=}}{{27293251 }} gab.com Text Role of Osteopontin in Psoriasis: An Immunohistochemical Study JO: Indian J Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=27293251 #FOAvip BACKGROUND: Osteopontin (OPN) has been postulated to have a role in several T-helper (Th) 1 and Th 17-mediated diseases including psoriasis (PS), through multiple mechanisms sharing in the onset and worsening of PS, OPN shares in induction of keratinocyte proliferation through inhibiting keratinocyte apoptosis, OPN acts as a proinflammatory agent that participates in the upregulation of Th cell lineages, among which are the Th 1 and Th 17 cells. AIMS AND OBJECTIVES: The aim of this study was to explore the possible role of OPN in the pathogenesis of PS. MATERIALS AND METHODS: This case-control study was carried out on 18 patients of chronic plaque PS (mean age 37.61 ± 14.48) and a control group of 18 apparently healthy volunteers (mean age 41.11 ± 11.02 years). Severity of PS was assessed using the PS area and severity index score. Two skin biopsies were taken from psoriatic patients. The first was taken from the lesional skin and the other from a counter apparently healthy site. RESULTS: Our results showed statistically significant differences in the expression of OPN, between lesional and nonlesional skin as well as between nonlesional skin and control group (P ? 0.001). In addition, there was a significant difference in the expression of OPN, between control and lesional group. CONCLUSIONS: OPN involvement in PS enlarges the list of cytokines able to stimulate the inflammatory response in this disease, anti-OPN antibodies, may eventually become a useful therapeutic approach in PS. Twit Text FOAVip Role of Osteopontin in Psoriasis: An Immunohistochemical Study ????Indian J Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=27293251 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27293251 #FOAvip English Wikipedia <ref>{{Cite pmid|27293251 }}</ref> Role of Osteopontin in Psoriasis: An Immunohistochemical Study #MMPMID27293251 Abdel-Mawla MY ; El-Kasheshy KA ; Ghonemy S ; Al Balat W ; Elsayed AA Indian J Dermatol 2016[May]; 61 (3 ): 301-7 PMID27293251 show ga BACKGROUND: Osteopontin (OPN) has been postulated to have a role in several T-helper (Th) 1 and Th 17-mediated diseases including psoriasis (PS), through multiple mechanisms sharing in the onset and worsening of PS, OPN shares in induction of keratinocyte proliferation through inhibiting keratinocyte apoptosis, OPN acts as a proinflammatory agent that participates in the upregulation of Th cell lineages, among which are the Th 1 and Th 17 cells. AIMS AND OBJECTIVES: The aim of this study was to explore the possible role of OPN in the pathogenesis of PS. MATERIALS AND METHODS: This case-control study was carried out on 18 patients of chronic plaque PS (mean age 37.61 ± 14.48) and a control group of 18 apparently healthy volunteers (mean age 41.11 ± 11.02 years). Severity of PS was assessed using the PS area and severity index score. Two skin biopsies were taken from psoriatic patients. The first was taken from the lesional skin and the other from a counter apparently healthy site. RESULTS: Our results showed statistically significant differences in the expression of OPN, between lesional and nonlesional skin as well as between nonlesional skin and control group (P ? 0.001). In addition, there was a significant difference in the expression of OPN, between control and lesional group. CONCLUSIONS: OPN involvement in PS enlarges the list of cytokines able to stimulate the inflammatory response in this disease, anti-OPN antibodies, may eventually become a useful therapeutic approach in PS. äRole of Osteopontin in Psoriasis: An Immunohistochemical Study (epmc).pdf DeepDyve Pubget Overpricing